Can we run one eCommerce platform with multiple SAP systems?

From the Connector point of view, this is surely possible. If your eCommerce platform supports different websites, with separated configuration, it is possible to connect these to the different SAP Connectors. Each separate eCommerce website within the eCommerce platform, will be configured and connected to a specific SAP environment.

With this in mind, it would be – for example – possible to run websites in different countries. Or different business units within one eCommerce platform, that are connected to specific SAP environments. It is also possible to connect one SAP environment to multiple websites, within one eCommerce platform.